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7/4/2005

Good news for high blood pressure patients

A new way to keep blood pressure under control

If you have high b.p , then there is a good news for you. As new and advanced technique has been developed to keep blood pressure under control.

Chromogranin A (CHGA) is a hormone-like molecule that is overexpressed in hereditary hypertension, but its precise role in the disease was unclear.

In a new study appearing in the July 1 print issue of The Journal of Clinical Investigation, Sushil Mahata and colleagues from UCSD describe several novel phenotypes observed in mice lacking CHGA, and establish a role for this protein in hormone and neurotransmitter storage and release in vivo.

The mice had elevated blood pressure that could be restored to normalcy by treating the mice with human CHGA, demonstrating that the human gene plays a role in autonomic control of blood pressure. An accompanying commentary by Taeyoon Kim and Y. Peng Loh states that one important clinical implication of this work is that CHGA may be used as a therapeutic agent for treating hypertension in humans.

More: Indian News, Health News

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